cfDNA Key genomic markers in HCV-Induced hepatocellular carcinoma in Egyptian patients
The present study represents the first comprehensive somatic mutation profile in HCC Egyptian patients. This finding suggests that HCV viral infection played a direct and indirect role in increasing the somatic mutation burden in HCV-related HCC patients and opens new promises of targeted therapies for those patients.
Authors
- Ahmed R. Sofy (ORCID: https://orcid.org/0000-0003-2685-5851)
- Ahmed A. Hmed
- Sayed Bakry (ORCID: https://orcid.org/0000-0003-4198-0175)
- Manal El Hamshary
- Mohamed K. Khalifa (ORCID: https://orcid.org/0000-0002-1260-6726)
- Khaled S Elfeky
Institutions
- Al-Azhar University (EG)
- University of Sadat City (EG)
- Children Cancer Hospital (EG)
Publication Details
- Journal
- Journal of Genetic Engineering and Biotechnology
- Published
- 2025-07-18
- DOI
- https://doi.org/10.1016/j.jgeb.2025.100533
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00