Systematic Review And Meta Analysis On Prevalence Of Opticospinal Multiple Sclerosis In Asian Population

Multiple sclerosis is a chronic, inflammatory disorder of the central nervous system which is prevalent across the Western population. Employing current technologies, it has been discovered that a subtype of MS which results in severe damage of spinal cord and optic nerves exists in Asian populations. A binary random-effect meta-analysis carried out in the scope of this study illuminates the mean prevalence rate of OSMS in Asia, including studies from regions East Asia, Sound-East Asia, Central Asia, Middle Eastern. The findings estimated a mean prevalence ratio of around 0.340 of the selected 25 studies out of 117 screened studies with a confidence level of 95%. Regarding regional disparities in MS prevalence, Japan serves as an example of a country with moderate rates and a significant portion of the data used in this study is derived from the Japanese population. In contrast, countries within the Indian subcontinent, such as India and Pakistan, as well as certain Middle Eastern nations Iran and Oman, tend to exhibit lower MS prevalence rates.