Modulation of Antibody Glycosylation in Chinese Hamster Ovary Cells: An Experimental and Computational Study

Process conditions and cell culture media components significantly impact glycosylation in ways that are still poorly understood. Here, we evaluated the glycan distribution of CHO-K1 clones producing adalimumab, a biosimilar version of the anti-TNF an

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Publication Details

Published
2025-07-18
DOI
https://doi.org/10.22541/au.175282761.19335611/v1
Primary Topic
Viral Infectious Diseases and Gene Expression in Insects
Type
article
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article

Modulation of Antibody Glycosylation in Chinese Hamster Ovary Cells: An Experimental and Computational Study

Ioscani Jiménez del Val, Susan T. Sharfstein, Ranya Pranomphon, Montarop Yamabhai et al.
Viral Infectious Diseases and Gene Expression in Insects
article

Modulation of Antibody Glycosylation in Chinese Hamster Ovary Cells: An Experimental and Computational Study

Ioscani Jiménez del Val, Susan T. Sharfstein, Ranya Pranomphon, Montarop Yamabhai, Sofia Gialamoidou
article en

Abstract

Process conditions and cell culture media components significantly impact glycosylation in ways that are still poorly understood. Here, we evaluated the glycan distribution of CHO-K1 clones producing adalimumab, a biosimilar version of the anti-TNF an

University College Dublin (IE), University at Albany, State University of New York (US), Suranaree University of Technology (TH)
Zero hunger
Openalex Percentile: Top 82%
Viral Infectious Diseases and Gene Expression in Insects
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