Mechanistic Insights Into The Inhibitory Effects Of Epigallocatechin Gallate (EGCG) From Green Tea Extract On Colon Cancer

Epigallocatechin gallate (EGCG), the primary active ingredient in green tea, possesses multiple biological activities including antioxidant, anti - inflammatory, and anti - tumor properties. This study investigated the inhibitory effect of EGCG on colon cancer and its potential mechanism via cell experiments.The results indicated that EGCG markedly inhibited the proliferation, invasion, and migration of colon cancer cells and induced cell apoptosis.This study offers a theoretical foundation for the application of EGCG as a preventive and therapeutic agent for colon cancer.

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Publication Details

Journal
International Journal of Environmental Sciences
Published
2025-06-02
DOI
https://doi.org/10.64252/rbp8a625
Primary Topic
Tea Polyphenols and Effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Mechanistic Insights Into The Inhibitory Effects Of Epigallocatechin Gallate (EGCG) From Green Tea Extract On Colon Cancer

Dola Das, Liang Minghui, An Huichao
International Journal of Environmental Sciences
Tea Polyphenols and Effects
article

Mechanistic Insights Into The Inhibitory Effects Of Epigallocatechin Gallate (EGCG) From Green Tea Extract On Colon Cancer

Dola Das, Liang Minghui, An Huichao
article en

Abstract

Epigallocatechin gallate (EGCG), the primary active ingredient in green tea, possesses multiple biological activities including antioxidant, anti - inflammatory, and anti - tumor properties. This study investigated the inhibitory effect of EGCG on colon cancer and its potential mechanism via cell experiments.The results indicated that EGCG markedly inhibited the proliferation, invasion, and migration of colon cancer cells and induced cell apoptosis.This study offers a theoretical foundation for the application of EGCG as a preventive and therapeutic agent for colon cancer.

International Journal of Environmental Sciences
Good health and well-being
Openalex Percentile: Top 71%
Tea Polyphenols and Effects
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