Medicinal importance of <i>Emblica officinalis </i>leaf extract nanoparticles and their biological evaluation

Green Synthesis of Nanoparticles is a novel field of nanotechnology that outperforms both biological and chemical approaches in terms of biocompatibility, cost-efficiency, scalability and environmental friendliness. Bacteria, fungi, plant and algae have lately been used to produce metals and metal oxide nanoparticles as an alternate method. In the present study, the green synthesis of Silver and copper nanoparticles was carried out using leaf extract of Emblica officinalis as a reducing agent and their antibacterial activity against human pathogens. Biosynthesis of nanoparticles were carried out using methanolic leaves extract of Emblica officinalis. Nanoparticles were characterized by UV-Visible Spectroscopy, X-ray Diffraction patterns (XRD), Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). These biogenic particles were tested for antimicrobial activity by disc diffusion method against Escherichia coli & Staphylococcus aureus. Biosynthesized nanoparticles showed potent biological activity and effective radicals scavenging activity. Methanolic leaf extract of Emblica officinalis acts as an excellent capping agent for the formation of silver & copper nanoparticles and demonstrates immense biological activities. Hence, these particles can be used as antibacterial, antioxidant as well as cytotoxic agent in treating many medical complications. It can be concluded that the silver and copper nanoparticles constitute an effective antimicrobial agent against common pathogenic bacteria. This could be a significant achievement in contending with many dynamic pathogens.