Polygenic risk of refractory celiac disease type II and its association with autoimmune diseases: a phenome-wide association study in the UK Biobank
Our study identified an association between the genetic risk score for RCDII and ankylosing spondylitis, but not with other autoimmune diseases. This finding may have clinical importance for people with RCDII, although replication in future studies is needed.
Authors
- Konstantinos K. Tsilidis (ORCID: https://orcid.org/0000-0002-8452-8472)
- Maria Manou (ORCID: https://orcid.org/0000-0002-9584-0373)
- Christos V. Chalitsios (ORCID: https://orcid.org/0000-0002-0836-9385)
- Christopher Papandreou (ORCID: https://orcid.org/0000-0002-6803-507X)
- Lampriani Tsali (ORCID: https://orcid.org/0000-0002-1747-0872)
- Evangelia Ntzani (ORCID: https://orcid.org/0000-0003-3712-4181)
- Georgios Markozannes (ORCID: https://orcid.org/0000-0001-8481-579X)
- Konstantinos Κarmiris (ORCID: https://orcid.org/0000-0003-3552-3074)
Institutions
- Rhode Island Department of Health (US)
- University of Ioannina (GR)
- Mediterranean University (ME)
- University of Oxford (GB)
- Institut de Recerca Biomèdica Catalunya Sud (ES)
- Department of Health Services (US)
- Imperial College London (GB)
Publication Details
- Journal
- European Journal of Gastroenterology & Hepatology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1097/meg.0000000000003036
- Citations
- 1
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.81