Combination of Montelukast Sodium and Fexofenadine HCL: A Comprehensive Overview of Efficacy and Safety in Allergy and Asthma Management

Allergic conditions and asthma significantly impact the quality of life and require effective managementstrategies. Montelukast sodium, a leukotriene receptor antagonist, and Fexofenadine HCL, a second-generation antihistamine, are widely used in allergy and asthma treatment. Their combination offers a dual mechanism of action that targets both histamine and leukotriene-mediated pathways, providing enhanced symptom relief. This review explores the pharmacological properties, clinical efficacy, safety profile, and potential benefits of this combination therapy. It highlights its role in improving respiratory function and controlling allergic reactions with minimal adverse effects.

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Publication Details

Published
2025-07-18
DOI
https://doi.org/10.38124/ijisrt/25apr1253
Primary Topic
Allergic Rhinitis and Sensitization
Type
article
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article

Combination of Montelukast Sodium and Fexofenadine HCL: A Comprehensive Overview of Efficacy and Safety in Allergy and Asthma Management

Chirag Patel, Khushbu Patel, Vishal Patel
2 links
Allergic Rhinitis and Sensitization
article

Combination of Montelukast Sodium and Fexofenadine HCL: A Comprehensive Overview of Efficacy and Safety in Allergy and Asthma Management

Chirag Patel, Khushbu Patel, Vishal Patel
article en

Abstract

Allergic conditions and asthma significantly impact the quality of life and require effective managementstrategies. Montelukast sodium, a leukotriene receptor antagonist, and Fexofenadine HCL, a second-generation antihistamine, are widely used in allergy and asthma treatment. Their combination offers a dual mechanism of action that targets both histamine and leukotriene-mediated pathways, providing enhanced symptom relief. This review explores the pharmacological properties, clinical efficacy, safety profile, and potential benefits of this combination therapy. It highlights its role in improving respiratory function and controlling allergic reactions with minimal adverse effects.

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Allergic Rhinitis and Sensitization
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