Management of Cardiogenic Shock: Therapeutic Strategiesx

Cardiogenic shock (CS) is one of the most critical syndromes in cardiovascular medicine, characterized by acute circulatory failure and high mortality, especially after acute myocardial infarction.This article carries out a narrative review of recent literature, focusing on the main pharmacological and mechanical therapeutic strategies applied in the management of CHF.Norepinephrine remains the vasopressor of choice, while the association with dobutamine can be useful in patients with severe ventricular dysfunction.Circulatory support devices such as ECMO--VA and Impella have been used in refractory cases, although with significant risks.Percutaneous revascularization of the culprit lesion remains the only intervention with a proven impact on clinical outcomes.The implementation of multidisciplinary teams and structured protocols has shown an improvement in survival, especially in specialized centers.Finally, the need for an individualized approach, based on clinical phenotype, biomarker stratification and advances such as artificial intelligence, is highlighted in order to overcome the persistent challenges in the management of CHD and reduce its high morbidity and mortality.

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Publication Details

Journal
International Journal of Health Science
Published
2025-07-14
DOI
https://doi.org/10.22533/at.ed.15952625140713
Primary Topic
Mechanical Circulatory Support Devices
Type
article
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article

Management of Cardiogenic Shock: Therapeutic Strategiesx

G.C. Souza, Roberta Da Rin Della Mora, Ronaldo Antunes Barros, Maria João Cardoso et al.
International Journal of Health Science
Mechanical Circulatory Support Devices
article

Management of Cardiogenic Shock: Therapeutic Strategiesx

G.C. Souza, Roberta Da Rin Della Mora, Ronaldo Antunes Barros, Maria João Cardoso, Ryan Rafael Barros de Macedo, Matheus Santos Machado, Rui Dinis Sousa, Camille Binda, Suzana de Oliveira Campos, G. Moura, Adriana dos Santos Estevam
article en

Abstract

Cardiogenic shock (CS) is one of the most critical syndromes in cardiovascular medicine, characterized by acute circulatory failure and high mortality, especially after acute myocardial infarction.This article carries out a narrative review of recent literature, focusing on the main pharmacological and mechanical therapeutic strategies applied in the management of CHF.Norepinephrine remains the vasopressor of choice, while the association with dobutamine can be useful in patients with severe ventricular dysfunction.Circulatory support devices such as ECMO--VA and Impella have been used in refractory cases, although with significant risks.Percutaneous revascularization of the culprit lesion remains the only intervention with a proven impact on clinical outcomes.The implementation of multidisciplinary teams and structured protocols has shown an improvement in survival, especially in specialized centers.Finally, the need for an individualized approach, based on clinical phenotype, biomarker stratification and advances such as artificial intelligence, is highlighted in order to overcome the persistent challenges in the management of CHD and reduce its high morbidity and mortality.

International Journal of Health ScienceVol. 5(26)
Good health and well-being
Openalex Percentile: Top 81%
Mechanical Circulatory Support Devices
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Management of Cardiogenic Shock: Therapeutic Strategiesx — G.C. Souza, Roberta Da Rin Della Mora, et al. · International Journal of Health Science (2025) | TGRS Research Map | TGRS