Converging lens radiotherapy (CLRT) employing kilovoltage x‐ray source: Treatment planning study

This study serves as a first proof-of-concept of the treatment capabilities of a novel CLRT x-ray system. The system demonstrated, in this limited set of plans, better OAR dose sparing compared to conventional Linac-based plans across 3 different anatomical sites, accompanied by similar, and possibly better, plan quality metrics (CI, TCI, CN, GI), while maintaining comparable target coverage.

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Publication Details

Journal
Medical Physics
Published
2025-08-01
DOI
https://doi.org/10.1002/mp.18007
Primary Topic
Advanced Radiotherapy Techniques
Type
article
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article

Converging lens radiotherapy (CLRT) employing kilovoltage x‐ray source: Treatment planning study

E Gebert, Piotr Zygmanski, D. Alezra, Jürgen Hesser et al.
Medical Physics
Advanced Radiotherapy Techniques
article

Converging lens radiotherapy (CLRT) employing kilovoltage x‐ray source: Treatment planning study

E Gebert, Piotr Zygmanski, D. Alezra, Jürgen Hesser, Marvin Kinz, Adi Alfassi
article en

Abstract

This study serves as a first proof-of-concept of the treatment capabilities of a novel CLRT x-ray system. The system demonstrated, in this limited set of plans, better OAR dose sparing compared to conventional Linac-based plans across 3 different anatomical sites, accompanied by similar, and possibly better, plan quality metrics (CI, TCI, CN, GI), while maintaining comparable target coverage.

Medical PhysicsVol. 52(8)
Brigham and Women's Hospital (US), Harvard University (US), University of Mannheim (DE), Heidelberg University (DE), University Hospital Heidelberg (DE), Dana-Farber Cancer Institute (US), The Radiosurgery Society (US), University Medical Centre Mannheim (DE), Dana-Farber Brigham Cancer Center (US), Heidelberg University (US)
Good health and well-being
Openalex Percentile: Top 73%
Advanced Radiotherapy Techniques
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Converging lens radiotherapy (CLRT) employing kilovoltage x‐ray source: Treatment planning study — E Gebert, Piotr Zygmanski, et al. · Medical Physics (2025) | TGRS Research Map | TGRS