Prevalence of genetic mutations in Alpha-1 antitrypsin in patients with difficult-to-treat asthma in Colombia
The study identified a prevalence of AAT mutations in 12.5% of adult patients with difficult-to-treat asthma in Colombia made up of four genotypes: M/S, M/Z, M/I and S/S.
Authors
- Claudia Diaz-Bossa
- Nadia Juliana Proaños (ORCID: https://orcid.org/0000-0002-4360-9604)
- Abraham Alí-Munive (ORCID: https://orcid.org/0000-0003-2153-0492)
- Leidy P. Prada (ORCID: https://orcid.org/0000-0002-6978-3600)
- John Carlos Pedrozo‐Pupo (ORCID: https://orcid.org/0000-0002-5675-7016)
- Angela Giraldo
- J Chacón
- Leslie Vargas
Institutions
- Universidad de La Sabana (CO)
- Technological University of Pereira (CO)
- University of Magdalena (CO)
- Instituto del Corazón de Bucaramanga (CO)
- Municipality of Medellín (CO)
- Fundación Neumológica Colombiana (CO)
- Universidad Católica de Pereira (CO)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1186/s12890-025-03840-5
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Universidad de La Sabana
- Grifols