From standardized to individualized margins for online adaptive tumor dose escalation in rectal cancer
Our study demonstrated that distance to anorectal junction significantly influenced the magnitude and direction of the intrafraction motion of rectal cancer patients receiving SCRT, with distal tumors showing larger motion in the AP and CC directions. For proximal rectal tumors, the margin could be decreased in AP and CC direction.
Authors
- Doenja M. J. Lambregts (ORCID: https://orcid.org/0000-0003-2990-0099)
- Corrie A.M. Marijnen (ORCID: https://orcid.org/0000-0003-0189-5953)
- C M Kensen
- Tomas Janssen (ORCID: https://orcid.org/0000-0003-2807-8670)
- Anja Betgen
- Lisa Wiersema
- Uulke A van der Heide
Institutions
- The Netherlands Cancer Institute (NL)
Publication Details
- Journal
- Radiation Oncology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1186/s13014-025-02706-8
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00