Multi-oocyte follicles in the bovine ovary: occurrence, activation, and growth during early in vitro folliculogenesis in a dynamic culture bioreactor
MOFs retain the capacity for early folliculogenesis comparable to SOFs, without increased atresia. Their stable frequency postculture supports a prenatal origin. These findings offer new insights into MOF biology and suggest a possible physiological relevance in mammalian reproductive systems.
Authors
- Angela Travaglione
- Andrea Candela (ORCID: https://orcid.org/0009-0000-6778-7686)
- Roberto Gualtieri (ORCID: https://orcid.org/0000-0002-0424-5254)
- Vincenzo Genovese
- Riccardo Talevi (ORCID: https://orcid.org/0000-0003-3767-5258)
- Vincenza De Gregorio (ORCID: https://orcid.org/0000-0002-7111-2961)
- M.C. Cimmino
Institutions
- University of Naples Federico II (IT)
Publication Details
- Journal
- Journal of Assisted Reproduction and Genetics
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1007/s10815-025-03600-8
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Napoli Federico II