Immunosuppression variably impacts outcomes for patients hospitalized with COVID-19: A retrospective cohort study
Patients with immunosuppression had worse outcomes than patients without immunosuppression. Subgroup analyses showed that patients with solid organ transplant had the worst outcomes overall. Patients with HIV had similar outcomes as patients without immunosuppression unless CD4 cell count was low.
Authors
- Jennifer A. Pacheco (ORCID: https://orcid.org/0000-0001-8021-5818)
- Anna Pawlowski (ORCID: https://orcid.org/0000-0002-9047-6437)
- Jodi Johnson (ORCID: https://orcid.org/0000-0002-8328-5587)
- Catherine A. Gao (ORCID: https://orcid.org/0000-0001-5576-3943)
- Grant R. Whitmer (ORCID: https://orcid.org/0000-0003-2421-2852)
- Alexandre Carvalho (ORCID: https://orcid.org/0000-0001-5683-3181)
- Theresa L. Walunas (ORCID: https://orcid.org/0000-0002-7653-3650)
- Chad J. Achenbach (ORCID: https://orcid.org/0000-0003-4847-7249)
- Vijeeth Guggilla (ORCID: https://orcid.org/0000-0001-9132-514X)
Institutions
- Northwestern University (US)
- Intel (United States) (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1371/journal.pone.0330110
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gilead Sciences
- Northwestern University
- National Institutes of Health
- National Center for Advancing Translational Sciences