Effects of Ageing, Oestrogen Level and Altered Dietary Loading on Rat Mandibular Cartilage—A Polarised Light Microscopy Study
Age and dietary loading significantly influenced collagen fibril orientation and retardance, with ageing generally leading to increased fibril orientation angles and often resulting in increased retardance. Dietary variations, particularly harder diets, emerged as a key factor with more substantial effects on collagen structure, affecting both fibre orientation and retardance.
Authors
- Lassi Rieppo (ORCID: https://orcid.org/0000-0001-5542-4060)
- Riikka Hauru (ORCID: https://orcid.org/0000-0002-0391-4612)
- Pertti Pirttiniemi (ORCID: https://orcid.org/0000-0003-4514-836X)
- Aune Raustia (ORCID: https://orcid.org/0000-0001-9644-4148)
- Anna‐Sofia Silvola (ORCID: https://orcid.org/0000-0003-2152-5140)
- Bijay Ratna Shakya (ORCID: https://orcid.org/0000-0002-3176-3081)
- Sakari Laaksonen (ORCID: https://orcid.org/0000-0003-2245-0822)
- Simo Saarakkala (ORCID: https://orcid.org/0000-0003-2850-5484)
- Jia Yu (ORCID: https://orcid.org/0000-0003-1293-0347)
Institutions
- Oulu University Hospital (FI)
- University of Oulu (FI)
- Air Force Medical University (CN)
Publication Details
- Journal
- Orthodontics and Craniofacial Research
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1111/ocr.70010
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Center Oulu
- Suomen Hammaslääkäriseura Apollonia
- Oulun Yliopisto
- Medical Research Council