Experimental investigation of oxygen diffusion in the peak and valley region of minibeam patterns during x‐ray irradiation

A novel way of simultaneously measuring oxygen in the peak and valley of the MB dose pattern was introduced. The observed oxygen depletion saturation and diffusion between the peaks and valleys suggest the importance of oxygen in spatially fractionated radiotherapy studies, which is even greater for 5 mM glutathione compared to water.

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Publication Details

Journal
Medical Physics
Published
2025-08-01
DOI
https://doi.org/10.1002/mp.17999
Primary Topic
Radiation Therapy and Dosimetry
Type
article
Field-Weighted Citation Impact
0.00

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article

Experimental investigation of oxygen diffusion in the peak and valley region of minibeam patterns during x‐ray irradiation

Joao Seco, Christina Stengl, Evelyn Rauth, Constantin Schorling
Medical Physics
Radiation Therapy and Dosimetry
article

Experimental investigation of oxygen diffusion in the peak and valley region of minibeam patterns during x‐ray irradiation

Joao Seco, Christina Stengl, Evelyn Rauth, Constantin Schorling
article en

Abstract

A novel way of simultaneously measuring oxygen in the peak and valley of the MB dose pattern was introduced. The observed oxygen depletion saturation and diffusion between the peaks and valleys suggest the importance of oxygen in spatially fractionated radiotherapy studies, which is even greater for 5 mM glutathione compared to water.

Medical PhysicsVol. 52(8)
German Cancer Research Center (DE), Heidelberg University (DE), University Hospital Heidelberg (DE)
Deutsche Krebshilfe
Clean water and sanitation
Openalex Percentile: Top 70%
Radiation Therapy and Dosimetry
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