Brief Report: Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Participants With Preexisting K65R/N in HIV-1 in Phase 2/3/3b Clinical Trials

Despite the presence of the TFV signature resistance mutation K65R/N, participants receiving B/F/TAF maintained virologic suppression demonstrating the efficacy of B/F/TAF in this population.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2025-08-08
DOI
https://doi.org/10.1097/qai.0000000000003742
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
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article

Brief Report: Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Participants With Preexisting K65R/N in HIV-1 in Phase 2/3/3b Clinical Trials

Michelle L. D’Antoni, Silvia D. Chang, Archana V. Boopathy, Kristen Andreatta et al.
1 links
JAIDS Journal of Acquired Immune Deficiency Syndromes
HIV/AIDS drug development and treatment
article

Brief Report: Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Participants With Preexisting K65R/N in HIV-1 in Phase 2/3/3b Clinical Trials

Michelle L. D’Antoni, Silvia D. Chang, Archana V. Boopathy, Kristen Andreatta, Jason T. Hindman, Christian Callebaut
article en

Abstract

Despite the presence of the TFV signature resistance mutation K65R/N, participants receiving B/F/TAF maintained virologic suppression demonstrating the efficacy of B/F/TAF in this population.

JAIDS Journal of Acquired Immune Deficiency SyndromesVol. 100(4)
Petra Christian University (ID), Gilead Sciences (United States) (US)
Good health and well-being
Openalex Percentile: Top 75%
HIV/AIDS drug development and treatment
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