Maternal Use of Antidepressants in Pregnancy and the Risk of Postpartum Hemorrhage: An Electronic Health Record‐Based Cohort Study
Prenatal S/NRI exposure was associated with an increased risk of PPH after adjusting for maternal depression, although residual confounding and confounding by other factors (including unmeasured factors) may be possible, as the risk of PPH appeared to be similar between S/NRI users and former users. Best-practice PPH risk management strategies should be adhered to for depressed patients, especially those who require treatment with antidepressants during pregnancy.
Authors
- Ardesheer Talati (ORCID: https://orcid.org/0000-0001-5708-1372)
- Katherine M. Moore (ORCID: https://orcid.org/0000-0003-0528-3209)
- William V. Bobo (ORCID: https://orcid.org/0000-0002-5674-3079)
- Cynthia Stoppel
- Hannah K. Betcher
- David O. Hodge (ORCID: https://orcid.org/0000-0001-5148-9174)
- Launia J. White (ORCID: https://orcid.org/0000-0003-0251-9431)
- Alyssa M. Larish
Institutions
- Mayo Clinic (US)
- Columbia University Irving Medical Center (US)
- Jacksonville College (US)
- WinnMed (US)
- New York Psychoanalytic Society and Institute (US)
- Mayo Clinic in Florida (US)
- New York State Psychiatric Institute
Publication Details
- Journal
- Human Psychopharmacology Clinical and Experimental
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1002/hup.70015
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 0.00