Obstacles in genetic testing for germline BRCA1/2 pathogenic mutations in patients with primary breast and ovarian cancer in Switzerland

Timely, well-communicated recommendations and informational resources significantly improve genetic counseling uptake among breast and ovarian cancer patients. Addressing systemic and patient-specific barriers will enhance equitable access, optimize targeted therapies and preventive strategies, and should be supported by national registries, qualitative research, and digital integration.

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Publication Details

Journal
Archives of Gynecology and Obstetrics
Published
2025-08-09
DOI
https://doi.org/10.1007/s00404-025-08138-9
Primary Topic
BRCA gene mutations in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Obstacles in genetic testing for germline BRCA1/2 pathogenic mutations in patients with primary breast and ovarian cancer in Switzerland

Christine Brambs, Lucie Krautova, Kathrin Schwedler, Christian Braun et al.
Archives of Gynecology and Obstetrics
BRCA gene mutations in cancer
article

Obstacles in genetic testing for germline BRCA1/2 pathogenic mutations in patients with primary breast and ovarian cancer in Switzerland

Christine Brambs, Lucie Krautova, Kathrin Schwedler, Christian Braun, Corina Christmann
article en

Abstract

Timely, well-communicated recommendations and informational resources significantly improve genetic counseling uptake among breast and ovarian cancer patients. Addressing systemic and patient-specific barriers will enhance equitable access, optimize targeted therapies and preventive strategies, and should be supported by national registries, qualitative research, and digital integration.

Archives of Gynecology and ObstetricsVol. 312(4)
University of Lucerne (CH), Luzerner Kantonsspital (CH)
Openalex Percentile: Top 78%
BRCA gene mutations in cancer
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Obstacles in genetic testing for germline BRCA1/2 pathogenic mutations in patients with primary breast and ovarian cancer in Switzerland — Christine Brambs, Lucie Krautova, et al. · Archives of Gynecology and Obstetrics (2025) | TGRS Research Map | TGRS