Change in the volume of choroidal plexus at the onset of a demyelinating disease

Choroidal plexuses (CPs) are particularly interesting due to their immunological activity and direct involvement in neuroinflammation in patients with multiple sclerosis (MS). Currently, MS pathogenesis has not been sufficiently studied, and the early stages of the disease, including radiologically isolated syndrome (RIS), are the most relevant ones for study. The CP volume is a new promising marker that can predict the transformation from preclinical forms of MS to the symptomatic form of the disease. The article presents a clinical case of RIS transformation to MS. During follow-up and neuroimaging, an increase in the volume of CS according to MRI morphometry was also revealed.