Mediating role of inflammatory markers in the relationship between cotinine levels and total bone mineral density
Smoking serves as a risk factor for reduced BMD, and the impact on BMD is partially mediated by inflammatory markers such as monocytes and neutrophils. Platelets can moderate the effect of cotinine on total BMD to some extent.
Authors
- Lei Huang (ORCID: https://orcid.org/0000-0002-4064-0518)
- Xianghong Wang (ORCID: https://orcid.org/0000-0002-0833-334X)
- Xianxu Zhang
- Biyun Qian (ORCID: https://orcid.org/0000-0003-4587-7300)
- Xin Liu (ORCID: https://orcid.org/0009-0009-6467-1560)
- Changlin Zhou (ORCID: https://orcid.org/0000-0001-5910-4259)
- Shicheng Li (ORCID: https://orcid.org/0000-0001-6296-636X)
- Zhiqiang Luo (ORCID: https://orcid.org/0000-0002-5651-3847)
- Zhong Ma
Institutions
- Jiuquan Iron & Steel (China) (CN)
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1371/journal.pone.0329062
- Primary Topic
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00