Isolated Central Nervous System Relapse in a Patient with FLT3-ITD Positive Acute Promyelocytic Leukemia

CNS relapse in APL, though rare, requires high clinical suspicion, particularly in patients with FLT3-ITD mutations. Early diagnosis using imaging and CSF analysis, followed by prompt intrathecal therapy, is crucial for effective management. This case highlights the need for vigilance in monitoring high-risk APL patients for CNS complications and emphasizes the importance of early intervention to improve outcomes.