A companion to the development of common data elements for Sudden Unexpected Death in Epilepsy (SUDEP)

Preclinical sudden unexpected death in epilepsy (SUDEP) research holds great promise for addressing this fatal condition; however, lack of data standardization remains an issue. Other fields have shown that the incorporation of common data elements (CDEs) can serve to harmonize data across groups, increase rigor, and improve translatability. An accompanying paper describes "Core" CDEs that could be used by all SUDEP preclinical researchers; the current manuscript describes related, supplemental CDEs applicable to researchers depending on their specific scientific question. These include neurological and physiological measures, therapeutics and pharmacology, neuroimaging, ex vivo electrophysiology, and additional phenotypes related to epilepsy.

Authors

Publication Details

Journal
Epilepsia Open
Published
2025-08-09
DOI
https://doi.org/10.1002/epi4.70103
Citations
4
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
5.88

Funders

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article

A companion to the development of common data elements for Sudden Unexpected Death in Epilepsy (SUDEP)

Laura S. Lubbers, Elaine O’Loughlin, Sloka Iyengar, Lauren C. Harte‐Hargrove et al.
4 citations
Epilepsia Open
Epilepsy research and treatment
5.88
article

A companion to the development of common data elements for Sudden Unexpected Death in Epilepsy (SUDEP)

Laura S. Lubbers, Elaine O’Loughlin, Sloka Iyengar, Lauren C. Harte‐Hargrove, Mary Holmay
article en
4 citations

Abstract

Preclinical sudden unexpected death in epilepsy (SUDEP) research holds great promise for addressing this fatal condition; however, lack of data standardization remains an issue. Other fields have shown that the incorporation of common data elements (CDEs) can serve to harmonize data across groups, increase rigor, and improve translatability. An accompanying paper describes "Core" CDEs that could be used by all SUDEP preclinical researchers; the current manuscript describes related, supplemental CDEs applicable to researchers depending on their specific scientific question. These include neurological and physiological measures, therapeutics and pharmacology, neuroimaging, ex vivo electrophysiology, and additional phenotypes related to epilepsy.

Epilepsia OpenVol. 10(5)
Citizens United for Research in Epilepsy, BAND foundation, National Institute of Neurological Disorders and Stroke
Openalex Percentile: Top 4%
Epilepsy research and treatment
5.88
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A companion to the development of common data elements for Sudden Unexpected Death in Epilepsy (SUDEP) — Laura S. Lubbers, Elaine O’Loughlin, et al. · Epilepsia Open (2025) | TGRS Research Map | TGRS