A companion to the development of common data elements for Sudden Unexpected Death in Epilepsy (SUDEP)
Preclinical sudden unexpected death in epilepsy (SUDEP) research holds great promise for addressing this fatal condition; however, lack of data standardization remains an issue. Other fields have shown that the incorporation of common data elements (CDEs) can serve to harmonize data across groups, increase rigor, and improve translatability. An accompanying paper describes "Core" CDEs that could be used by all SUDEP preclinical researchers; the current manuscript describes related, supplemental CDEs applicable to researchers depending on their specific scientific question. These include neurological and physiological measures, therapeutics and pharmacology, neuroimaging, ex vivo electrophysiology, and additional phenotypes related to epilepsy.
Authors
- Laura S. Lubbers (ORCID: https://orcid.org/0000-0002-1645-9356)
- Elaine O’Loughlin
- Sloka Iyengar (ORCID: https://orcid.org/0000-0003-4790-1466)
- Lauren C. Harte‐Hargrove (ORCID: https://orcid.org/0000-0001-5678-9184)
- Mary Holmay
Publication Details
- Journal
- Epilepsia Open
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1002/epi4.70103
- Citations
- 4
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.88
Funders
- Citizens United for Research in Epilepsy
- BAND foundation
- National Institute of Neurological Disorders and Stroke