Identifying key genes involved in HBV-related hepatocellular carcinoma: diagnose, prognosis, interaction and immune analysis
Six hug-genes are closely related to the HBV-HCC development, which involved in multiple biological progress and immune infiltration. Among them, NDC80, CDK1, EZH2 could severed as markers with good diagnostic and prognostic value. Notably, several approved drugs interaction with hub genes might be potential drug used for HBV-HCC therapy.
Authors
- Siyu Liu (ORCID: https://orcid.org/0000-0001-8049-7771)
- Rui-Cheng Li
- H.-N. Qian
- Yan Li (ORCID: https://orcid.org/0000-0003-1813-8115)
- Jing Hu (ORCID: https://orcid.org/0009-0007-8446-0862)
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Tang Du Hospital (CN)
- Henan Medical University (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1007/s12672-025-03320-6
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shaanxi Province