Mendelian Randomization Study of Sex Hormone Binding Globulin and Its Influence on Adverse Pregnancy Outcomes
Our study indicated that the increased levels of SHBG could significantly reduce the risk of APO. SHBG may be helpful as the indicator for preconception risk assessment and pregnancy risk monitoring. These findings are limited to European and require further validation in diverse populations.
Authors
- Qiuhui Pan (ORCID: https://orcid.org/0000-0003-0261-7082)
- Feng Cheng (ORCID: https://orcid.org/0000-0003-3196-434X)
- Y. Jin
- Han Wu
- Chaoyan Yue (ORCID: https://orcid.org/0000-0002-0597-8388)
Institutions
- Fujian Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai Mental Health Center (CN)
- Fujian Women and Children Hospital (CN)
- Shanghai Children's Medical Center (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- American Journal of Reproductive Immunology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1111/aji.70139
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province