Posttreatment toxicity following single-fraction versus multifraction hypofractionated stereotactic radiosurgery for larger meningiomas
When controlling for tumor volume, despite higher treatment doses in the hSRS group relative to the SRS group, posttreatment toxicity was not significantly different between the groups, and freedom from local failure was improved in the hSRS group. For patients with larger meningiomas, multifraction hSRS may help to limit the risk of posttreatment edema and toxicity, while maintaining acceptable freedom from local failure.
Authors
- Rebecca Calafiore (ORCID: https://orcid.org/0000-0003-1567-1942)
- Carol Kittel (ORCID: https://orcid.org/0000-0002-4512-0634)
- Michael T. Munley
- Adrian W. Laxton (ORCID: https://orcid.org/0000-0002-4631-5476)
- Michael D. Chan (ORCID: https://orcid.org/0000-0002-5278-6709)
- Christina K. Cramer (ORCID: https://orcid.org/0000-0001-7618-3921)
- Stephen B. Tatter (ORCID: https://orcid.org/0000-0002-1063-0431)
- R Christensen
- Eleanor Smith (ORCID: https://orcid.org/0000-0001-8502-8974)
- Jaclyn J. White
Institutions
- Wake Forest University (US)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2025-08-09
- DOI
- https://doi.org/10.3171/2025.4.jns242824
- Citations
- 1
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 1.35