Evaluation of the effectiveness of intensive medical rehabilitation in MS patients through the prism of functional tests and serum neurofilaments

The study's results confirm that intensive medical rehabilitation improves motor and cognitive functions in patients with MS but does not significantly affect the NF level, which indicates predominantly functional rather than structural changes in the nervous system. It emphasized the importance of a combined approach to MS management, including drug therapy and medical rehabilitative interventions. Studies with larger samples and more sensitive NF analysis methods, such as Simoa, are needed to further investigate the effect of medical rehabilitation on neurodegenerative processes.

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Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2025-08-08
DOI
https://doi.org/10.17116/jnevro202512507279
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
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article

Evaluation of the effectiveness of intensive medical rehabilitation in MS patients through the prism of functional tests and serum neurofilaments

А. N. Boyko, С А Сиверцева, V. D. Chukreev, O. N. Novikova et al.
S S Korsakov Journal of Neurology and Psychiatry
Multiple Sclerosis Research Studies
article

Evaluation of the effectiveness of intensive medical rehabilitation in MS patients through the prism of functional tests and serum neurofilaments

А. N. Boyko, С А Сиверцева, V. D. Chukreev, O. N. Novikova, I.V. Yurovskikh
article en

Abstract

The study's results confirm that intensive medical rehabilitation improves motor and cognitive functions in patients with MS but does not significantly affect the NF level, which indicates predominantly functional rather than structural changes in the nervous system. It emphasized the importance of a combined approach to MS management, including drug therapy and medical rehabilitative interventions. Studies with larger samples and more sensitive NF analysis methods, such as Simoa, are needed to further investigate the effect of medical rehabilitation on neurodegenerative processes.

S S Korsakov Journal of Neurology and PsychiatryVol. 125(7)
Pirogov Russian National Research Medical University (RU), Clinical Institute of Brain (RU), Ural State Medical University (RU), JSS Medical Research (India) (IN), Kirov State Medical Academy (RU), Tyumen State Medical University (RU), Federal Medical-Biological Agency (RU)
Openalex Percentile: Top 71%
Multiple Sclerosis Research Studies
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Evaluation of the effectiveness of intensive medical rehabilitation in MS patients through the prism of functional tests and serum neurofilaments — А. N. Boyko, С А Сиверцева, et al. · S S Korsakov Journal of Neurology and Psychiatry (2025) | TGRS Research Map | TGRS