Late‐onset temporal lobe epilepsy: Enlarged amygdala‐hippocampus indicates interictal epileptic activity at electroencephalography and memory impairment
The present study provides the supporting findings for the association of amygdala-hippocampal enlargement with IED and memory impairment in late-onset TLE, suggesting that amygdala-hippocampal enlargement is a clinically significant indicator of epileptic excitability and memory impairment.
Authors
- Maya Tojima (ORCID: https://orcid.org/0000-0002-2715-1410)
- Kozue Hayashi
- Frank Leypoldt (ORCID: https://orcid.org/0000-0002-8972-515X)
- M. Honda (ORCID: https://orcid.org/0000-0002-7534-206X)
- Riki Matsumoto (ORCID: https://orcid.org/0000-0003-3985-9210)
- Hirofumi Takeyama (ORCID: https://orcid.org/0000-0002-1941-8293)
- Klaus‐Peter Wandinger (ORCID: https://orcid.org/0000-0002-5483-4276)
- Atsushi Shima (ORCID: https://orcid.org/0000-0002-3068-4621)
- Yuji Nakamoto (ORCID: https://orcid.org/0000-0001-5783-8048)
- Yasutaka Fushimi (ORCID: https://orcid.org/0000-0002-1982-3168)
- Kiyohide Usami (ORCID: https://orcid.org/0000-0003-2257-8279)
- Nobukatsu Sawamoto (ORCID: https://orcid.org/0000-0001-8695-0223)
- Tomohiko Murai (ORCID: https://orcid.org/0000-0001-7144-1848)
- Ryōsuke Takahashi (ORCID: https://orcid.org/0000-0002-1407-9640)
- Mitsuhiro Sakamoto
- Akio Ikeda
Institutions
- Kyoto University (JP)
- Rakuwakai Otowa Hospital (JP)
- Kyoto City Hospital (JP)
- University Hospital Schleswig-Holstein (DE)
- Otsu Red Cross Hospital (JP)
- Kobe University (JP)
- University of Lübeck (DE)
Publication Details
- Journal
- Epileptic Disorders
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1002/epd2.70061
- Citations
- 3
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.73
Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Japan Epilepsy Research Foundation