Deformable image registration of dark‐field chest radiographs for functional lung assessment

Our regional characterization of lung dark-field signal changes between the breathing states via deformable image registration provides a proof-of-principle that dynamic radiography-based lung function assessment approaches may benefit from considering registered dark-field images in addition to standard plain chest radiographs. This opens up new options for low-dose and rapid lung ventilation assessment via dark-field chest radiography that has the potential to improve lung diagnostics considerably.

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Publication Details

Journal
Medical Physics
Published
2025-08-01
DOI
https://doi.org/10.1002/mp.18023
Primary Topic
Advanced X-ray Imaging Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

Deformable image registration of dark‐field chest radiographs for functional lung assessment

Henriette Bast, Daniela Pfeiffer, Vasiliki Sideri‐Lampretsa, Thomas Koehler et al.
Medical Physics
Advanced X-ray Imaging Techniques
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Deformable image registration of dark‐field chest radiographs for functional lung assessment

Henriette Bast, Daniela Pfeiffer, Vasiliki Sideri‐Lampretsa, Thomas Koehler, Florian T. Gassert, Alexander Wolfgang Marka, Daniel Rueckert, Fabian Drexel
article en

Abstract

Our regional characterization of lung dark-field signal changes between the breathing states via deformable image registration provides a proof-of-principle that dynamic radiography-based lung function assessment approaches may benefit from considering registered dark-field images in addition to standard plain chest radiographs. This opens up new options for low-dose and rapid lung ventilation assessment via dark-field chest radiography that has the potential to improve lung diagnostics considerably.

Medical PhysicsVol. 52(8)
TUM Klinikum (DE), Institute for Advanced Study (DE), Philips (Germany) (DE), Munich Center for Machine Learning, Imperial College London (GB), Technical University of Munich (DE)
Australian Government, Bundesministerium für Bildung und Forschung, Technische Universität München, Centre for Advanced Laser Applications, European Research Council
Openalex Percentile: Top 73%
Advanced X-ray Imaging Techniques
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