Cardiometabolic risk stratification in pediatric obesity: evaluating the clinical utility of fasting insulin and BMI-SDS
In children and adolescents with obesity, fasting insulin provides complementary information to BMI-SDS in identifying those with elevated cardiometabolic risk factors. While neither marker alone offers strong predictive accuracy, incorporating fasting insulin into clinical assessment may help prioritize individuals who require more detailed evaluation. An elevated fasting insulin value may warrant further investigation among children and adolescents with obesity, independent of obesity class based on BMI-SDS.
Authors
- Banu Küçükemre Aydın (ORCID: https://orcid.org/0000-0003-0859-1565)
- Julian Gomahr
- Sara Y. Cerenius (ORCID: https://orcid.org/0000-0002-3131-2096)
- Hannes Manell (ORCID: https://orcid.org/0000-0002-5209-4841)
- Sami El Amrani (ORCID: https://orcid.org/0000-0003-1520-2636)
- Stefan Karl James (ORCID: https://orcid.org/0000-0003-4413-9736)
- Iris Ciba (ORCID: https://orcid.org/0000-0002-5062-8192)
- Julia Lischka (ORCID: https://orcid.org/0000-0002-7047-3829)
- Anders Forslund (ORCID: https://orcid.org/0000-0001-9109-4556)
- Thomas Pixner (ORCID: https://orcid.org/0000-0002-0407-3683)
- Rasmus Stenlid (ORCID: https://orcid.org/0000-0002-1586-9310)
- Daniel Weghuber (ORCID: https://orcid.org/0000-0002-4389-0379)
- Katharina Mörwald (ORCID: https://orcid.org/0000-0003-2945-3196)
- Peter Bergsten
Institutions
- Uppsala University (SE)
- Paracelsus Medical University (AT)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1186/s12933-025-02882-7
- Citations
- 1
- Primary Topic
- Obesity, Physical Activity, Diet
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Gillbergska stiftelsen
- Regionala Forskningsrådet Uppsala/Örebro
- Vetenskapsrådet
- Stiftelsen Familjen Ernfors Fond
- Seventh Framework Programme