The hemolytic activity of ABO antibodies: Correlation between quantitative tests, complement‐mediated hemolysis assay (CHUHE‐P), and IgG subclasses
This study aimed to compare the ability of anti-ABO antibodies to cause complement-mediated hemolysis measured by the CHUHE-P test and the results of semi-quantitative/quantitative titration assays, the presence of IgG1 and/or IgG3, and hemolysin test results, where we highlighted an inconsistent association between the methods; the positivity for CHUHE-P was associated with the subclasses of antibodies IgG1 and IgG3.
Authors
- José Orlando Bordin (ORCID: https://orcid.org/0000-0002-0324-6175)
- Thamy Caroline S Silva
- Glaciano Ribeiro (ORCID: https://orcid.org/0000-0002-0933-0562)
- Carla Luana Dinardo (ORCID: https://orcid.org/0000-0002-0453-7863)
- Karen Chinoca Ziza
- Dante Mário Langhi (ORCID: https://orcid.org/0000-0002-4642-8091)
- Sidneia Sanches de Menezes Costa (ORCID: https://orcid.org/0000-0001-6684-890X)
- Beatriz Girardo
Institutions
- Instituto de Medicina Avançada (BR)
- Fundação Pró-Sangue Hemocentro de São Paulo (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Transfusion Medicine
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1111/tme.70005
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00