Identification of host-microbiome interactions in nasal diseases using multiomics integration.
Our findings delineate disease-specific microbiome-host interplay in nasal pathologies, with CRSwNP exhibiting immune-focused interactions versus NIP's proliferative associations. These insights advance our understanding of nasal disease mechanisms and support the development of targeted microbiome-modulating therapies.
Authors
- Wenjian Sun (ORCID: https://orcid.org/0000-0003-1584-8242)
- Zhi Liang Jiang (ORCID: https://orcid.org/0000-0003-0964-6791)
- Jing Li (ORCID: https://orcid.org/0009-0003-2507-1606)
- Ji Liu (ORCID: https://orcid.org/0000-0002-1763-0039)
- Fei Zhang (ORCID: https://orcid.org/0009-0008-7957-5937)
- Zhizhong Li (ORCID: https://orcid.org/0000-0002-9571-9311)
- Liang Yu (ORCID: https://orcid.org/0009-0007-3922-3454)
- Zi‐Jiang Chen (ORCID: https://orcid.org/0000-0001-6637-6631)
- Chen‐Yu Zhang (ORCID: https://orcid.org/0000-0002-7329-7162)
Institutions
- Tianjin First Center Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-12-01
- DOI
- https://doi.org/10.4193/rhin24.386
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00