A Novel Optical Coherence Tomography–based Keratoconus Diagnostic Index Incorporating Stromal and Epithelial Features

Individual OCT-based machine-derived parameters lack sufficient power to discriminate FFKC and EKC from normal corneas, but this can be improved by combining OCT-based information from stroma and epithelium as in this new index. The discrimination accuracy of the WISE index was comparable to existing Scheimpflug-based indices.

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Publication Details

Journal
Journal of Refractive Surgery
Published
2025-08-01
DOI
https://doi.org/10.3928/1081597x-20250602-02
Citations
2
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
2.72
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OCT
article

A Novel Optical Coherence Tomography–based Keratoconus Diagnostic Index Incorporating Stromal and Epithelial Features

Shihao Chen, J. Rozema, Nan‐Ji Lu, Qin-Mei Wang et al.
2 citations
Journal of Refractive Surgery
Corneal surgery and disorders
2.72
article

A Novel Optical Coherence Tomography–based Keratoconus Diagnostic Index Incorporating Stromal and Epithelial Features

Shihao Chen, J. Rozema, Nan‐Ji Lu, Qin-Mei Wang, Lele Cui, Sorcha Ní Dhubhghaill, Carina Koppen
article en
2 citations

Abstract

Individual OCT-based machine-derived parameters lack sufficient power to discriminate FFKC and EKC from normal corneas, but this can be improved by combining OCT-based information from stroma and epithelium as in this new index. The discrimination accuracy of the WISE index was comparable to existing Scheimpflug-based indices.

Journal of Refractive SurgeryVol. 41(8)
Vrije Universiteit Brussel (BE), University of Antwerp (BE), Sichuan University (CN), West China Hospital of Sichuan University (CN), Antwerp University Hospital (BE)
Reduced inequalities, Peace, Justice and strong institutions
Openalex Percentile: Top 9%
Corneal surgery and disorders
2.72
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A Novel Optical Coherence Tomography–based Keratoconus Diagnostic Index Incorporating Stromal and Epithelial Features — Shihao Chen, J. Rozema, et al. · Journal of Refractive Surgery (2025) | TGRS Research Map | TGRS