Discovery of Furan-tethered Triazolothiadiazoles and Triazolothiadiazines as Potent Tyrosinase Inhibitors for the Treatment of Skin Diseases: Insights from Kinetics Data and Computational Modeling
Additionally, the pharmacokinetic profile of these compounds highlighted promising drug-like properties, making them potential candidates for the development of effective therapeutics for skin disorders.
Authors
- Sumera Zaib (ORCID: https://orcid.org/0000-0002-9443-2191)
- Sobia Ahsan Halim (ORCID: https://orcid.org/0000-0001-8526-7799)
- Majid Khan (ORCID: https://orcid.org/0000-0002-9287-2046)
- Afnan Jan
- Magda H. Abdellattif (ORCID: https://orcid.org/0000-0002-8562-4749)
- Ahmed Al‐Harrasi (ORCID: https://orcid.org/0000-0002-0815-5942)
- Aliya Ibrar (ORCID: https://orcid.org/0000-0002-1954-0432)
- Atta Ullah (ORCID: https://orcid.org/0009-0003-1582-9460)
- Imtiaz Khan (ORCID: https://orcid.org/0000-0001-5331-110X)
- Ajmal Khan (ORCID: https://orcid.org/0000-0001-9703-2428)
- Humaira Hussian
Institutions
- Taif University (SA)
- University of Central Punjab (PK)
- Korea University (KR)
- Umm al-Qura University (SA)
- University of Nizwa (OM)
- University of Haripur (PK)
- University of Manchester (GB)
- Abbottabad University of Science and Technology (PK)
- Korea University (JP)
- University of Malakand (PK)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2025-08-08
- DOI
- https://doi.org/10.2174/0109298673349818250302105830
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.00