Efficacy of Non‐Ablative Fractional Laser Combined With Tranexamic Acid in Melasma Treatment: A Randomized Split‐Face Trial
The combination of NAFL and topical TXA provides significant short-term clinical benefits in treating melasma, likely by enhancing TXA penetration into target tissues and improving pigmentary clearance. However, its efficacy diminishes over time due to the inevitable recurrence of melasma, necessitating further investigation into long-term maintenance strategies.
Authors
- Pedram Noormohammadpour (ORCID: https://orcid.org/0000-0003-2503-2968)
- Mina Koohian Mohammadabadi
- Amirhossein Rahimnia (ORCID: https://orcid.org/0000-0002-4451-4930)
- Amir Houshang Ehsani (ORCID: https://orcid.org/0000-0002-5483-1163)
- Zahra Shadlou
- Motahareh Hosnian
- Ala Ehsani
Institutions
- Iran University of Medical Sciences (IR)
- Razi Hospital (IR)
- Shahid Beheshti University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1111/jocd.70384
- Citations
- 2
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 4.01