Vascular Risk Factors and 1-Year Cognitive Change Among Individuals With Traumatic Brain Injury
In this cohort study of individuals with TBI, those with diabetes displayed poorer global cognitive function and executive functioning 2 weeks after TBI and recovered less in processing speed over the first-year postinjury. Given the modifiable nature of comorbid vascular risk factors, future work interrogating postinjury changes in vascular risk factor burden, over longer follow-up, is warranted.
Authors
- Michael McCrea
- Lindsay D. Nelson (ORCID: https://orcid.org/0000-0001-5258-953X)
- David M. Schnyer (ORCID: https://orcid.org/0000-0002-7472-2853)
- Raquel C. Gardner (ORCID: https://orcid.org/0000-0003-4028-440X)
- Laura B. Ngwenya (ORCID: https://orcid.org/0000-0001-7103-971X)
- Ross Zafonte (ORCID: https://orcid.org/0000-0002-1050-796X)
- Patrick Belton
- Danielle K. Sandsmark (ORCID: https://orcid.org/0000-0002-1586-6961)
- Ramon Diaz‐Arrastia (ORCID: https://orcid.org/0000-0001-6051-3594)
- Andrea L.C. Schneider (ORCID: https://orcid.org/0000-0003-0026-5052)
- C. Dirk Keene (ORCID: https://orcid.org/0000-0002-5291-1469)
- Sonia Jain (ORCID: https://orcid.org/0000-0001-8408-1247)
- Ramesh Grandhi (ORCID: https://orcid.org/0000-0001-9000-6083)
- Pratik Mukherjee (ORCID: https://orcid.org/0000-0001-7473-7409)
- Shawn R. Eagle (ORCID: https://orcid.org/0000-0001-6767-1042)
- Katherine J. Hunzinger (ORCID: https://orcid.org/0000-0002-4599-8543)
- Benjamin L. Brett (ORCID: https://orcid.org/0000-0003-2849-4658)
- Vijay Krishnamoorthy (ORCID: https://orcid.org/0000-0002-1365-4121)
- Sabrina R. Taylor (ORCID: https://orcid.org/0000-0003-4867-1922)
- Claudia Sue Robertson (ORCID: https://orcid.org/0000-0002-8509-678X)
- Geoffrey A. Manley (ORCID: https://orcid.org/0000-0002-4950-4651)
- John K. Yue (ORCID: https://orcid.org/0000-0001-9694-7722)
- Shankar P. Gopinath (ORCID: https://orcid.org/0000-0002-5631-1364)
- Christine Mac Donald
- Randall E. Merchant
- David O. Okonkwo
- Xiaoying Sun
Institutions
- University of Wisconsin–Madison (US)
- Harvard University (US)
- Thomas Jefferson University (US)
- University of Pittsburgh (US)
- Duke University (US)
- University of California, San Francisco (US)
- Baylor College of Medicine (US)
- Virginia Commonwealth University (US)
- University of Washington (US)
- Medical College of Wisconsin (US)
- University of Utah (US)
- Sheba Medical Center (IL)
- NanoAffix Science (United States) (US)
- Human Longevity (United States) (US)
- Seattle University (US)
- University of Cincinnati (US)
- University of Pennsylvania (US)
- The University of Texas at Austin (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.25719
- Citations
- 3
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 4.06