PPDPF promotes the progression of esophageal squamous cell carcinoma via c-Myc/CD24 axis

PPDPF acts as an oncoprotein in ESCC by positively regulating the c-Myc/CD24 axis. These findings provide a potential effective target for immunotherapy in ESCC.

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Publication Details

Journal
Journal for ImmunoTherapy of Cancer
Published
2025-08-01
DOI
https://doi.org/10.1136/jitc-2025-012044
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
0.00

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article

PPDPF promotes the progression of esophageal squamous cell carcinoma via c-Myc/CD24 axis

Bing Zhu, Lin Qiu, Xiran Zhang, Qian‐Wen Zheng et al.
1 links
Journal for ImmunoTherapy of Cancer
Pancreatic and Hepatic Oncology Research
article

PPDPF promotes the progression of esophageal squamous cell carcinoma via c-Myc/CD24 axis

Bing Zhu, Lin Qiu, Xiran Zhang, Qian‐Wen Zheng, Xiang Wang, Lingyun Long, Zhigang Li, Jing‐Jing Li, Xiaosong Qiu, Xin Liang, Yi‐Kang Wang, Yan‐Jun Xiang, Kai Ding, Hui‐Jun Cao, Qian‐Zhi Ni, Wei Chen, Yao Fan, Zhichao Liu, Sheng Xu, Jing-Yi Huang, Yu Chen, Ji Xia, Ning Ma
article en

Abstract

PPDPF acts as an oncoprotein in ESCC by positively regulating the c-Myc/CD24 axis. These findings provide a potential effective target for immunotherapy in ESCC.

Journal for ImmunoTherapy of CancerVol. 13(8)
Second Military Medical University (CN), Shanghai Jiao Tong University (CN), Huazhong Agricultural University (CN), Sir Run Run Shaw Hospital (CN), Shanghai Chest Hospital (CN), ShanghaiTech University (CN), Shanghai Institute of Nutrition and Health (CN), Lishui Central Hospital (CN), China National Center for Food Safety Risk Assessment (CN), Eastern Hepatobiliary Surgery Hospital (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN), University of Chinese Academy of Sciences (CN), Zhejiang University (CN)
National Natural Science Foundation of China, Youth Innovation Promotion Association of the Chinese Academy of Sciences
No poverty
Openalex Percentile: Top 71%
Pancreatic and Hepatic Oncology Research
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