PPDPF promotes the progression of esophageal squamous cell carcinoma via c-Myc/CD24 axis
PPDPF acts as an oncoprotein in ESCC by positively regulating the c-Myc/CD24 axis. These findings provide a potential effective target for immunotherapy in ESCC.
Authors
- Bing Zhu (ORCID: https://orcid.org/0000-0003-2049-432X)
- Lin Qiu (ORCID: https://orcid.org/0009-0000-7199-6421)
- Xiran Zhang
- Qian‐Wen Zheng
- Xiang Wang (ORCID: https://orcid.org/0000-0003-0440-6203)
- Lingyun Long (ORCID: https://orcid.org/0000-0002-8064-832X)
- Zhigang Li (ORCID: https://orcid.org/0000-0001-5086-5334)
- Jing‐Jing Li (ORCID: https://orcid.org/0000-0002-3973-5405)
- Xiaosong Qiu
- Xin Liang (ORCID: https://orcid.org/0000-0001-7915-8094)
- Yi‐Kang Wang
- Yan‐Jun Xiang (ORCID: https://orcid.org/0000-0002-7378-6724)
- Kai Ding (ORCID: https://orcid.org/0000-0002-5412-5453)
- Hui‐Jun Cao
- Qian‐Zhi Ni (ORCID: https://orcid.org/0000-0002-4659-7696)
- Wei Chen (ORCID: https://orcid.org/0000-0003-4610-8490)
- Yao Fan
- Zhichao Liu (ORCID: https://orcid.org/0000-0003-3542-0905)
- Sheng Xu (ORCID: https://orcid.org/0000-0003-1781-0061)
- Jing-Yi Huang
- Yu Chen (ORCID: https://orcid.org/0009-0002-6247-1417)
- Ji Xia (ORCID: https://orcid.org/0000-0001-6228-1096)
- Ning Ma (ORCID: https://orcid.org/0000-0001-5578-3805)
Institutions
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Huazhong Agricultural University (CN)
- Sir Run Run Shaw Hospital (CN)
- Shanghai Chest Hospital (CN)
- ShanghaiTech University (CN)
- Shanghai Institute of Nutrition and Health (CN)
- Lishui Central Hospital (CN)
- China National Center for Food Safety Risk Assessment (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- University of Chinese Academy of Sciences (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1136/jitc-2025-012044
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Youth Innovation Promotion Association of the Chinese Academy of Sciences