Fragment-Based Screening Identifies Novel Non-Amino Acid Inhibitors of the Sodium-Coupled Neutral Amino Acid Transporter SNAT2
In conclusion, we discovered multiple novel non-amino acid compounds that inhibited SNAT2 and can serve as starting points for the further development of SNAT2 inhibitors.
Authors
- Carsten Uhd Nielsen (ORCID: https://orcid.org/0000-0001-5776-6865)
- Sebastian Jakobsen (ORCID: https://orcid.org/0000-0001-8341-4564)
Institutions
- University of Southern Denmark (DK)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1007/s11095-025-03902-7
- Primary Topic
- Amino Acid Enzymes and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Carlsbergfondet
- Syddansk Universitet
- Danmarks Frie Forskningsfond