Anti-adhesive glycoconjugates against <i>Candida albicans</i> : effect of the aromatic substituents in anti-fungal activity
Aromatic glycoconjugates with specific structural features, particularly lipophilic and compact substituents, show promise as anti-adhesion agents against C. albicans. These findings support the potential of anti-virulence strategies targeting fungal adhesion as alternatives to traditional fungicidal therapies.
Authors
- Cristina Trujillo (ORCID: https://orcid.org/0000-0001-9178-5146)
- Trinidad Velasco‐Torrijos (ORCID: https://orcid.org/0000-0002-0701-8268)
- Kevin Kavanagh (ORCID: https://orcid.org/0000-0003-3186-0292)
- Laia Moreno
- Diana Bura (ORCID: https://orcid.org/0000-0001-6729-5411)
- Keela Kessie (ORCID: https://orcid.org/0000-0001-8750-0435)
- Kyle Doherty (ORCID: https://orcid.org/0000-0003-2574-0331)
Institutions
- National University of Ireland, Maynooth (IE)
- Trinity College Dublin (IE)
- University of Manchester (GB)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-07-18
- DOI
- https://doi.org/10.1080/17568919.2025.2540274
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science Foundation Ireland