Liver X Receptor Activation Alleviates Hepatic Ischemia‐Reperfusion Injury in Diabetes by Inhibiting NF‐κB–NLRP3 Activation
LXRs play an important role in diabetic liver IRI and macrophage-associated inflammation. Pharmacologic activation of LXRs alleviates macrophage inflammatory activation in diabetic liver IRI, and may serve as a potential therapeutic target for diabetes-related liver injury.
Authors
- Chuanwei Jiang
- Wenzhou Ding (ORCID: https://orcid.org/0009-0003-3734-7112)
- Chao Yang (ORCID: https://orcid.org/0000-0003-0210-7648)
- Yuanchang Hu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Jiangsu Cancer Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/iid3.70243
- Citations
- 1
- Primary Topic
- Cholesterol and Lipid Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.01