Context is everything: The role of polo-like kinase I during <i>C. elegans</i> oocyte meiosis
Meiotic chromosome segregation in oocytes often relies on meiosis-specific modifications of mitotic molecular mechanisms to respond to the unique challenges of this asymmetric division. In this issue, Narula and Wignall (https://doi.org/10.1083/jcb.202503080) demonstrate how the conserved polo-like kinase in Caenorhabditiselegans, PLK-1, has been repurposed in unexpected ways to ensure accurate meiotic chromosome segregation during oogenesis.
Authors
- Needhi Bhalla (ORCID: https://orcid.org/0000-0002-6859-0073)
Institutions
- University of California, Santa Cruz (US)
Publication Details
- Journal
- The Journal of Cell Biology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1083/jcb.202506208
- Citations
- 1
- Primary Topic
- Microtubule and mitosis dynamics
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Institutes of Health