Molecular characterization of Echinocandin resistance and the CHS3-mediated adaptive response in Candida glabrata bloodstream infections in Eastern China
Our findings suggest that CHS3 plays a critical compensatory role in echinocandin resistance in C. glabrata, offering a promising target for developing future antifungal strategies.
Authors
- Guirong Sun (ORCID: https://orcid.org/0000-0003-3069-5811)
- Liu Ji (ORCID: https://orcid.org/0000-0002-6120-1282)
- Hong He (ORCID: https://orcid.org/0000-0002-2342-8750)
- Hui Guo (ORCID: https://orcid.org/0000-0002-6839-6238)
- Xiaoying Li (ORCID: https://orcid.org/0000-0002-6005-4620)
- Biao Wang (ORCID: https://orcid.org/0000-0002-8655-6258)
- Lijing Peng (ORCID: https://orcid.org/0000-0002-3033-4322)
- Peishan Cong
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Weifang Chinese Medicine Hospital (CN)
- Qingdao Women and Children's Hospital (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1186/s12866-025-04155-5
- Citations
- 1
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 1.40