Positive Predictive Value of Tissue Transglutaminase IgA for Celiac Disease
Elevated tTG IgA in isolation is insufficient to confidently diagnose celiac disease. As tTG assay performance varied widely, diagnostic confirmation by a specialist prior to dietary changes is essential.
Authors
- Marisa G. Stahl (ORCID: https://orcid.org/0000-0002-9656-5561)
- Ankur Chugh (ORCID: https://orcid.org/0000-0002-1106-3440)
- Dale Lee (ORCID: https://orcid.org/0000-0001-8148-3988)
- Catherine Raber (ORCID: https://orcid.org/0000-0003-2832-8860)
- Edwin Liu (ORCID: https://orcid.org/0000-0003-3591-8922)
- Michael S. Caplan (ORCID: https://orcid.org/0000-0003-3498-3503)
- Justine Turner (ORCID: https://orcid.org/0000-0002-3517-636X)
- Vahe Badalyan (ORCID: https://orcid.org/0000-0002-1361-2079)
- Arunjot Singh (ORCID: https://orcid.org/0000-0003-3642-0827)
- Maureen M. Leonard (ORCID: https://orcid.org/0000-0002-5955-5102)
- Catharine M. Walsh (ORCID: https://orcid.org/0000-0003-3928-703X)
- Mala Setty (ORCID: https://orcid.org/0000-0003-2809-3248)
- Dominica Gidrewicz (ORCID: https://orcid.org/0000-0002-5846-9472)
- Jocelyn A. Silvester (ORCID: https://orcid.org/0000-0002-3615-1666)
- Jane A. Dickerson (ORCID: https://orcid.org/0000-0003-0033-2892)
- María C. Cárdenas (ORCID: https://orcid.org/0000-0003-4166-5378)
- Denis Chang (ORCID: https://orcid.org/0000-0002-3843-5785)
- Imad Absah (ORCID: https://orcid.org/0000-0002-7565-870X)
- Lisa M. Fahey (ORCID: https://orcid.org/0000-0003-0651-5761)
- James A. King (ORCID: https://orcid.org/0000-0003-1332-3610)
- Madison Wong
- Cho-Ok Baek (ORCID: https://orcid.org/0009-0009-9727-334X)
- M. Cristina Pacheco
Institutions
- Children's Hospital of Wisconsin (US)
- Alberta Health Services (CA)
- Boston Children's Hospital (US)
- Mayo Clinic (US)
- Children's Hospital of Philadelphia (US)
- Alberta Children's Hospital (CA)
- WinnMed (US)
- Children's Hospital Colorado (US)
- Seattle Children's Hospital (US)
- Mayo Clinic in Arizona (US)
- UCSF Benioff Children's Hospital (US)
- Alberta Health (CA)
- Mayo Clinic in Florida (US)
- The Wilson Centre (CA)
- Stollery Children's Hospital (CA)
- University of Colorado Anschutz Medical Campus (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- PEDIATRICS
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1542/peds.2025-070897
- Citations
- 1
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.81