Evaluation of end-to-end 3D absorbed dose distribution in 90Y-SIRT and SBRT combination therapy using MAGIC-f polymer gel dosimeter
This is the first study demonstrating the feasibility of using MAGIC-f gel dosimetry to directly measure 3D dose distributions from combined <sup>90</sup>Y-SIRT and SBRT. Compared to PET/CT-based dosimetry, the gel method offers superior spatial resolution and enables objective physical verification of complex dose distributions. This technique has strong potential for quality assurance in theranostic protocols, particularly for beta emitters and, potentially, alpha-emitting radiotracers in future applications.
Authors
- Yazdan Salimi (ORCID: https://orcid.org/0000-0002-1233-9576)
- Habib Zaidi (ORCID: https://orcid.org/0000-0001-7559-5297)
- Nikolaos Koutsouvelis (ORCID: https://orcid.org/0000-0002-9343-8540)
- Zahra Mansouri (ORCID: https://orcid.org/0000-0003-4967-3970)
Institutions
- Obuda University (HU)
- University Medical Center Groningen (NL)
- University of Southern Denmark (DK)
- University Hospital of Geneva (CH)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1007/s00259-025-07461-2
- Citations
- 1
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Université de Genève
- Centre d'Imagerie BioMédicale