Epidermal Interferon‐κ Drives Cutaneous Lupus‐Like Lesions, Photosensitivity, and Systemic Autoimmunity In Vivo
Together, we describe a new CLE mouse model that recapitulates features of human CLE and substantiates the role of epidermal IFNκ as a driver of CLE, photosensitivity, and systemic inflammation.
Authors
- Céline C. Berthier (ORCID: https://orcid.org/0000-0003-3539-1075)
- Benjamin Klein (ORCID: https://orcid.org/0000-0002-3412-5536)
- Svenja Henning (ORCID: https://orcid.org/0000-0002-7895-6729)
- Kelsey E. McNeely
- Mehrnaz Gharaee‐Kermani (ORCID: https://orcid.org/0000-0002-2177-2427)
- Jacob William Shelton Martens
- Johann Eli Gudjonsson (ORCID: https://orcid.org/0000-0002-0080-0812)
- Joanne Michelle Kahlenberg (ORCID: https://orcid.org/0000-0002-4006-8945)
- Lori Lowe (ORCID: https://orcid.org/0000-0002-2359-8426)
- Jeffrey B. Hodgin (ORCID: https://orcid.org/0000-0003-0534-3048)
- Paul H. O’Brien
- Nguyen Thi Nguyen
- Lin Zhang (ORCID: https://orcid.org/0009-0000-0177-4647)
- Yiqing Gao
- Deborah J. Colesa
Institutions
- University of Michigan (US)
- Michigan United (US)
- Michigan Medicine (US)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1002/art.43350
- Citations
- 4
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 6.67