Kapβ2 Reverses Sevoflurane‐Induced Hydrogel Phase Transition of hnRNPA2/B1‐SG in Hypoxic Primary Rat Hippocampal Neurons
The hydrogel phase transition of hnRNPA2/B1-SG is a key pathological mechanism of sevoflurane-induced hippocampal neuronal injury. Kapβ2 may serve as a potential therapeutic target to counteract sevoflurane-related neurotoxicity.
Authors
- Huihui Liao
- Zixuan Wang (ORCID: https://orcid.org/0000-0002-3199-3418)
- Chenyi Yang (ORCID: https://orcid.org/0000-0002-7299-3668)
- M Zhang (ORCID: https://orcid.org/0009-0003-2510-2150)
- Feiyu Jia
- Lin Zhang (ORCID: https://orcid.org/0000-0003-0424-9965)
- Haiyun Wang (ORCID: https://orcid.org/0000-0002-0084-2342)
- Xi Xin (ORCID: https://orcid.org/0000-0003-3873-9145)
- Xinyi Wang (ORCID: https://orcid.org/0009-0003-5429-9853)
Institutions
- Tianjin University of Technology (CN)
- Nankai University (CN)
- Tianjin Third Central Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1111/cns.70532
- Citations
- 1
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China