Age of menopause and dementia risk in 10,832 women from the Swedish Twin Registry
We found a U-shaped association of timing of spontaneous menopause and dementia risk. We also found a negative linear association of age of induced menopause and dementia risk. Restriction to a hormone-naïve sample did not alter the pattern of results. Conducted exploration of the impact of common survival model parameter choices on results.
Authors
- Erin E. Sundermann (ORCID: https://orcid.org/0000-0001-5821-8035)
- Ursula G. Saelzler (ORCID: https://orcid.org/0000-0001-7853-1416)
- Nancy L. Pederson
- Margaret Gatz (ORCID: https://orcid.org/0000-0002-1071-9970)
- Matthew S. Panizzon (ORCID: https://orcid.org/0000-0002-6449-2097)
- Janelle T. Foret (ORCID: https://orcid.org/0000-0002-0463-2596)
- Ida Karlsson (ORCID: https://orcid.org/0000-0003-3605-7829)
Institutions
- University of Southern California (US)
- Karolinska Institutet (SE)
- University of California San Diego (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/alz.70541
- Citations
- 3
- Primary Topic
- Menopause: Health Impacts and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.88
Funders
- Karolinska Institutet
- Vetenskapsrådet
- National Institutes of Health