Clinical Analysis of Children with Mixed Macrolide-Resistant Mycoplasma Pneumoniae InfectionResearch Article

Purpose: To retrospectively evaluate the clinical characteristics of mixed macrolide-resistant mycoplasma pneumonia infections in children. Methods: The study included 167 hospitalized children with macrolide-resistant mycoplasma pneumonia. We analyzed the children's clinical data retrospectively, and compared the differences in the use of antibiotics, fever, hospitalization time, laboratory tests and complications between the mixed infection group and the separately infected group before admission. Results: Compared with the separately infected group, hospitalized children with mixed infection had a longer hospital stay, and there was a significant difference between the two (P<0.05); ALT, AST, LDH, CK, and PLT of children in the mixed infection group were significantly higher than those in the separately infected group (P<0.05); and the incidence of hepatic function impairment, cardiac enzyme profile abnormality, and pleural effusion in the children in the mixed infection group was higher than that in the separately infected group (P<0.01 ). Conclusion: Patients with macrolide-resistant Mycoplasma pneumoniae pneumonia combined with mixed infections had prolonged hospital stays, increased systemic inflammatory response, and increased incidence of extrapulmonary complications compared with those with simple infections.