Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification (Adv. Sci. 29/2025)
LabeL-Free DiagnosisThe artwork highlights a breakthrough method for detecting and quantifying global DNA methylation.This highly sensitive approach leverages in situ surface growth of plasmonic particles to enable molecular trapping and label-free sensing.Combined with machine learning analysis, it allows precise quantification of global methylation levels, offering a promising strategy for early cancer diagnosis and comprehensive epigenetic profiling.More details can be found in article number 2503257 by Min-Young Lee, Ho Sang Jung, and co-workers
Authors
- Muhammad Shalahuddin Al Ja’farawy (ORCID: https://orcid.org/0000-0003-3130-0228)
- Vo Thi Nhat Linh
- Ho Sang Jung (ORCID: https://orcid.org/0000-0003-1776-1802)
- Rowoon Park
- ChaeWon Mun
- Sung‐Gyu Park (ORCID: https://orcid.org/0000-0002-0580-3211)
- Jun-Young Yang (ORCID: https://orcid.org/0000-0001-7751-4534)
- Min‐Young Lee (ORCID: https://orcid.org/0000-0003-3396-7632)
- Dongho Kim (ORCID: https://orcid.org/0000-0001-8668-2644)
- Jun Young Kim (ORCID: https://orcid.org/0000-0001-7878-4616)
Publication Details
- Journal
- Advanced Science
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/advs.71025
- Primary Topic
- Advanced Proteomics Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00