The Transcriptional Coactivator DEAD/H Box 5 (DDX5) Gene Is a Target of the Transcription Factor E2F1 Deregulated from the Tumor Suppressor pRB
These results suggest that the <i>DDX5</i> gene is a target of deregulated E2F1, generating a feed forward loop mediating tumor suppressive E2F1 activity.
Authors
- Andrew P. Bradford (ORCID: https://orcid.org/0000-0002-8728-571X)
- Yaxuan Zhou (ORCID: https://orcid.org/0009-0009-2593-3572)
- Mashiro Shirasawa (ORCID: https://orcid.org/0009-0000-5743-7842)
- Kenta Kurayoshi (ORCID: https://orcid.org/0009-0008-8194-0489)
- Rinka Nakajima (ORCID: https://orcid.org/0009-0000-3222-7590)
- Ritsuko Iwanaga (ORCID: https://orcid.org/0009-0008-1142-4753)
- Mariana Fikriyanti
- Keigo Araki (ORCID: https://orcid.org/0000-0002-4771-0494)
- Kiyoshi Ohtani
Institutions
- Kanazawa University (JP)
- Kwansei Gakuin University (JP)
- Ohu University (JP)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Genes
- Published
- 2025-08-01
- DOI
- https://doi.org/10.3390/genes16080929
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Yoshida Scholarship Foundation
- Ministry of Education, Culture, Sports, Science and Technology
- Japan Science Society
- TOBE MAKI Scholarship Foundation