A RARE ENCOUNTER: LISTERIA MONOCYTOGENES AND BRAIN ABSCESS

Listeriosis, caused by Listeria Monocytogenes, is a serious yet rare illness caused by consuming contaminated food and is considered a global public threat. Central nervous system (CNS) involvement often follows bacteraemia; common clinical presentation is usually meningitis. Listeria brain abscess is an uncommon pathology and can manifest in various clinical presentations, with fever and focal neurological deficits being the most common. Brain abscess secondary to listeria is associated with high mortality. We present a rare case of a 68-year-old immunocompromised female who developed a cerebral abscess due to Listeria monocytogenes. The presence of fever, increased somnolence prompted further investigation. This case underscores the need for brain imaging in the evaluation of listeria sepsis, even when clinical presentations are atypical. Additionally, in cases without major neurological deficits or swelling, postponing abscess drainage may be considered. A cautious approach with IV antibiotics, repeat imaging and close monitoring can be offered to patients who are unwilling to undergo aspiration and drainage of brain abscess or are poor surgical candidates.

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Journal
Journal of Ayub Medical College Abbottabad
Published
2025-03-15
DOI
https://doi.org/10.55519/jamc-01-13907
Primary Topic
Listeria monocytogenes in Food Safety
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article
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article

A RARE ENCOUNTER: LISTERIA MONOCYTOGENES AND BRAIN ABSCESS

Iffat Khanum, Amany M. Haroon, Amara Zafar, Ibtesam Ishrat
Journal of Ayub Medical College Abbottabad
Listeria monocytogenes in Food Safety
article

A RARE ENCOUNTER: LISTERIA MONOCYTOGENES AND BRAIN ABSCESS

Iffat Khanum, Amany M. Haroon, Amara Zafar, Ibtesam Ishrat
article en

Abstract

Listeriosis, caused by Listeria Monocytogenes, is a serious yet rare illness caused by consuming contaminated food and is considered a global public threat. Central nervous system (CNS) involvement often follows bacteraemia; common clinical presentation is usually meningitis. Listeria brain abscess is an uncommon pathology and can manifest in various clinical presentations, with fever and focal neurological deficits being the most common. Brain abscess secondary to listeria is associated with high mortality. We present a rare case of a 68-year-old immunocompromised female who developed a cerebral abscess due to Listeria monocytogenes. The presence of fever, increased somnolence prompted further investigation. This case underscores the need for brain imaging in the evaluation of listeria sepsis, even when clinical presentations are atypical. Additionally, in cases without major neurological deficits or swelling, postponing abscess drainage may be considered. A cautious approach with IV antibiotics, repeat imaging and close monitoring can be offered to patients who are unwilling to undergo aspiration and drainage of brain abscess or are poor surgical candidates.

Journal of Ayub Medical College AbbottabadVol. 37(1)
Aga Khan University Hospital (PK)
Openalex Percentile: Top 77%
Listeria monocytogenes in Food Safety
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A RARE ENCOUNTER: LISTERIA MONOCYTOGENES AND BRAIN ABSCESS — Iffat Khanum, Amany M. Haroon, et al. · Journal of Ayub Medical College Abbottabad (2025) | TGRS Research Map | TGRS